Nutraferon Imeron Injection - Liquid Dosage Form Imipenem + Cilastatin Ingredients | Broad Spectrum Antibiotic For Serious Bacterial Infections In Adults

Imipenem and cilastatin injection is used to treat certain serious infections that are caused by bacteria including endocarditis (infection of the heart lining and valves) and respiratory tract (including pneumonia) urinary tract abdominal (stomach area) gynecological blood skin bone and joint infections Because imipenem is rapidly inactivated by renal dehydropeptidase I (DHP-1) it is given in combination with cilastatin a DHP-I inhibitor which increases half-life and tissue penetration of imipenem. Imipenem + Cilastatin is a combination of two medicines: Imipenem and Cilastatin. Imipenem is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Cilastatin is dehydropeptidase I inhibitor which blocks the activity of an enzyme (dehydropeptidase I) that causes breakdown of Imipenem . Hence it helps Imipenem stay active in your body for a longer period of time. Imipenem is a broad spectrum carbapenem antibiotic which is used for severe bacterial infections caused by susceptible organisms. Because imipenem is rapidly inactivated by renal dehydropeptidase I (DHP-1) it is given in combination with cilastatin a DHP-I inhibitor which increases half-life and tissue penetration of imipenem. Parenterally administered imipenem/cilastatin has been associated with transient mild serum aminotransferase elevations but it is a rare cause of clinically apparent liver disease with jaundice.